Published on: March 10, 2026 | Updated on: March 17, 2026
Chronic knee pain is one of the most common joint problems in the US. It is closely tied to knee osteoarthritis (OA), which alone affects at least 19% of American adults aged 45 and older.
Instead of removing and replacing damaged joint surfaces through surgery, many patients are now turning to regenerative treatments like stem cell therapy. The process involves injecting concentrated cells, taken from a patient’s own bone marrow or fat tissue, directly into the knee. These cells can help reduce inflammation and improve joint function.
Let’s explore how stem cell knee therapy works, its benefits, and its cost.
What Does Stem Cell Knee Surgery Include?
Stem cell therapy for knee issues does not involve any traditional surgery. There are no large incisions, implants, or joint replacements. Instead, it’s a regenerative treatment that uses biologic injections to support healing inside the knee joint.
The goal is to reduce pain and improve function without removing or replacing damaged bone and cartilage.
Most providers use bone marrow aspirate concentrate (BMAC), usually obtained from the hip, and process it to concentrate specific cells. This concentrate contains mesenchymal stem cells (MSCs), some growth factors, and other supportive cells. MSCs are known to help regulate inflammation and support tissue repair.
Some clinics may also use cells taken from the patient’s fat tissue. After preparation, the concentrated cells are injected directly into the knee joint.
Conditions Treated by Stem Cell Knee Surgery
If you’re dealing with knee osteoarthritis, stem cell therapy could be a game-changer for you. It’s the main reason people turn to this treatment, as studies show it helps ease your pain and boost knee function over just a few months, outperforming placebos or standard care.
One meta-analysis found that patients experienced large drops in pain scores at 3, 6, and even 12 months after receiving mesenchymal stem cell injections directly into the joint. You’ll also feel more mobile for daily activities, and early-stage OA responds especially well since the cells kickstart your cartilage repair.
Stem cells also help with cartilage damage and meniscal tears in your knee. These issues can wear down your joints over time, but stem cell therapy uses your own cells to promote healing and slow degeneration.
If you’ve got partial meniscal damage or focal cartilage wear from injury or overuse, stem cell therapy can also help delay worse breakdown, keeping you active without jumping to surgery. Patients in recent studies often report smoother movement and less stiffness after just a few sessions.
How Does the Stem Cell Knee Surgery Procedure Work
The stem cell knee surgery procedure in Las Vegas starts with a detailed evaluation.
The provider reviews your medical history, current symptoms, prior treatments, and imaging studies. This will help them determine whether the joint damage is mild, moderate, or advanced. Patients with severe bone-on-bone arthritis are not as suitable for stem cell therapy.
If you are a candidate, the next step is cell sourcing. In autologous treatment, the doctor will extract the cells from your own body, usually from bone marrow in the hip. The sample is processed in a centrifuge to create bone marrow aspirate concentrate (BMAC), which contains mesenchymal stem cells and growth factors.
Then, the doctor injects the concentrated cells directly into the knee joint. Many patients return to light daily activities within a few days, but it’s best to avoid strenuous exercise for several weeks. Pain relief can take weeks to months, and follow-up visits are often scheduled to monitor progress.
How Much Does Stem Cell Knee Surgery Cost?
For stem cell knee surgery in Las Vegas, you’re looking at costs typically between $4,000 and $8,000 per knee. However, the exact price depends on the clinic, cell type, and how many sessions you need, which is often just one or two for great results.
In general, most patients pay between $5,000 and $12,000 per knee for high-quality treatments. However, you may need to pay out of pocket since insurance doesn’t cover stem cell therapy.
If you’re in Las Vegas, you can expect similar pricing, typically $5,000 to $15,000 per knee. Factors like the doctor’s experience and extras such as follow-ups or rehab support can increase the costs. Still, it’s much cheaper than a full knee replacement, which can cost $20,000 or more with hospital stays.
Is Stem Cell Knee Surgery Right For You?
If you’re struggling with osteoarthritis or cartilage wear and want a natural way to ease pain without surgery, stem cell knee therapy may be right for you. You’ll likely notice less stiffness and better daily mobility if your OA is moderate (like grade 2 or 3) and you’ve tried basics like PT or injections without full relief, since the cells promote healing right where you need it.
It can be especially promising if you’re active and hoping to delay bigger fixes, as many clinical trials show improvements in joint scores and cartilage signals without serious side effects. Additionally, you can opt for stem cell therapy if your knee pain limits sports or work and imaging shows repairable damage.
On the other hand, if your knee damage is in the later stages, like grade 4 OA with bone-on-bone grinding or major deformities, you may need to opt for conventional surgery. Even then, stem cell therapy can prep your joint and speed recovery post-op.
Finding Reputable Stem Cell Knee Surgery Clinics in Las Vegas
Choosing a stem cell clinic in Las Vegas should not come down to price alone. Here are some tips to help you make a better choice:
- Confirming the provider is board-certified and experienced in orthopedic or regenerative medicine.
- Ask what type of cells are being used (your own bone marrow or donor tissue) and how they are processed.
- Make sure they review your imaging, explain realistic outcomes, and use ultrasound or fluoroscopy to guide injections for accuracy.
- Beware of clinics that promise guaranteed cartilage regrowth or push treatment without a full evaluation.
If you want a clinic that focuses on precision, transparency, and physician-led care, schedule a consultation with CELLAXYS to see if you’re a candidate.
Sources
Footnotes
- Andersen RE, Crespo CJ, Ling SM, Bathon JM, Bartlett SJ. Prevalence of significant knee pain among older Americans: results from the Third National Health and Nutrition Examination Survey. Journal of the American Geriatrics Society. 1999 Dec.
- Orozco L, Munar A, Soler R, Alberca M, Soler F, Huguet M, Sentís J, Sánchez A, García-Sancho J. Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study. Transplantation. 2013 Jun.
- Huang R, Li W, Zhao Y, Yang F, Xu M. Clinical efficacy and safety of stem cell therapy for knee osteoarthritis: A meta-analysis. Medicine. 2020 Mar.
- Wiggers TG, Winters M, Van den Boom NA, Haisma HJ, Moen MH. Autologous stem cell therapy in knee osteoarthritis: a systematic review of randomised controlled trials. British Journal of Sports Medicine. 2021 Oct.
References
- Stem Cell Therapy for Knees: Explained (2025). DVC Stem. Accessed 2/26/2026.
- Stem cell therapy cost 2020. DVC Stem. Accessed 2/17/2026.
- What are the benefits and risks of stem cell injections for knee osteoarthritis? Cochrane. Accessed 2/26/2026.
- Stem cell therapy: an alternative for osteoarthritis of the knee. Southwest Healthcare. Accessed 2/26/2026.
CELLAXYS does not offer Stem Cell Therapy as a cure for any medical condition. No statements or treatments presented by Cellaxys have been evaluated or approved by the Food and Drug Administration (FDA). This site contains no medical advice. All statements and opinions are provided for educational and informational purposes only.
Dr Pouya Mohajer
Author
Pouya Mohajer, M.D. is the Director of Spine and Interventional Medicine for CELLAXYS: Age, Regenerative, and Interventional Medicine Centers. He has over 20 years of experience in pain management, perioperative medicine, and anesthesiology. Dr. Mohajer founded and is the Medical Director of Southern Nevada Pain Specialists and PRIMMED Clinics. He has dedicated his career to surgical innovation and scientific advancement. More about the doctor on this page.
Dr Pejman Bady
Contributor
Dr. Pejman Bady began his career over 20 years ago in Family/Emergency Medicine, working in fast-paced emergency departments in Nevada and Kansas. He has served the people of Las Vegas as a physician for over two decades. Throughout this time, he has been met with much acclaim and is now the head of Emergency Medical Services in Nye County, Nevada. More about the doctor on this page.




